Vacuolar ion channels in the liverwort Marchantia polymorpha: influence of ion channel inhibitors
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DOI: 10.1007/s00425-017-2661-4
Abstract: AbstractMain conclusionPotassium-permeable slow activating vacuolar channels (SV) and chloride-permeable channels in the vacuole of the liverwortMarchantia polymorphawere characterized in respect to calcium dependence, selectivity, and pharmacology. The patch-clamp method was used in the study of… read more here.
Keywords: permeable channels; channel inhibitors; ion channel; channel ... See more keywords
Plasma membrane Ca2+-permeable channels and sodium/calcium exchangers in tumorigenesis and tumor development of the upper gastrointestinal tract.
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DOI: 10.1016/j.canlet.2020.01.026
Abstract: The upper gastrointestinal (GI) tumors are multifactorial diseases associated with a combination of oncogenes and environmental factors. Currently, surgery, chemotherapy, radiotherapy and immunotherapy are relatively effective treatment options for the patients with these tumors. However,… read more here.
Keywords: permeable channels; channels sodium; plasma membrane; ca2 ... See more keywords
A subset of taste receptor cells express biocytin‐permeable channels activated by reducing extracellular Ca2+ concentration
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DOI: 10.1111/ejn.14672
Abstract: Taste receptor cells (type II cells) transmit taste information to taste nerve fibres via ATP‐permeable channels, including calcium homeostasis modulator (CALHM), connexin and/or pannexin1 channels, via the paracrine release of adenosine triphosphate (ATP) as a… read more here.
Keywords: taste; permeable channels; biocytin permeable; biocytin ... See more keywords
Structural and Functional Coupling of Calcium-Activated BK Channels and Calcium-Permeable Channels Within Nanodomain Signaling Complexes
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DOI: 10.3389/fphys.2021.796540
Abstract: Biochemical and functional studies of ion channels have shown that many of these integral membrane proteins form macromolecular signaling complexes by physically associating with many other proteins. These macromolecular signaling complexes ensure specificity and proper… read more here.
Keywords: calcium; ca2 permeable; signaling complexes; permeable channels ... See more keywords
Role of Pannexin 1 ATP-Permeable Channels in the Regulation of Signaling Pathways during Skeletal Muscle Unloading
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DOI: 10.3390/ijms221910444
Abstract: Skeletal muscle unloading results in atrophy. We hypothesized that pannexin 1 ATP-permeable channel (PANX1) is involved in the response of muscle to unloading. We tested this hypothesis by blocking PANX1, which regulates efflux of ATP… read more here.
Keywords: permeable channels; skeletal muscle; muscle; pannexin atp ... See more keywords
Role of K+ and Ca2+-Permeable Channels in Osteoblast Functions
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DOI: 10.3390/ijms221910459
Abstract: Bone-forming cells or osteoblasts play an important role in bone modeling and remodeling processes. Osteoblast differentiation or osteoblastogenesis is orchestrated by multiple intracellular signaling pathways (e.g., bone morphogenetic proteins (BMP) and Wnt signaling pathways) and… read more here.
Keywords: permeable channels; lineage cells; role; osteoblast lineage ... See more keywords