Cell-Permeable Succinate Rescues Mitochondrial Respiration in Cellular Models of Amiodarone Toxicity
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DOI: 10.3390/ijms222111786
Abstract: Amiodarone is a potent antiarrhythmic drug and displays substantial liver toxicity in humans. It has previously been demonstrated that amiodarone and its metabolite (desethylamiodarone, DEA) can inhibit mitochondrial function, particularly complexes I (CI) and II… read more here.
Keywords: mitochondrial respiration; cell permeable; respiration; permeable succinate ... See more keywords