Carnosine protects cardiac myocytes against lipid peroxidation products
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2676-6
Abstract: Endogenous histidyl dipeptides such as carnosine (β-alanine-l-histidine) form conjugates with lipid peroxidation products such as 4-hydroxy-trans-2-nonenal (HNE and acrolein), chelate metals, and protect against myocardial ischemic injury. Nevertheless, it is unclear whether these peptides protect… read more here.
Keywords: cardiac myocytes; lipid peroxidation; peroxidation products; carnosine ... See more keywords
Lipid Peroxidation Products HNE and ONE Promote and Stabilize Alpha-Synuclein Oligomers by Chemical Modifications.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry"
DOI: 10.1021/acs.biochem.1c00478
Abstract: The aggregation of α-synuclein (αSN) and increased oxidative stress leading to lipid peroxidation are pathological characteristics of Parkinson's disease (PD). Here, we report that aggregation of αSN in the presence of lipid peroxidation products 4-hydroxy-2-nonenal… read more here.
Keywords: aggregation; lipid peroxidation; peroxidation; peroxidation products ... See more keywords
Lipid Peroxidation Products Influence Calpain-1 Functionality In Vitro by Covalent Binding.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c01225
Abstract: The objective of the current study was to evaluate the effects of lipid peroxidation products, malondialdehyde (MDA), hexenal, and 4-hydroxynonenal (HNE), on calpain-1 function, and liquid chromatography and tandem mass spectrometry (LC-MS/MS) identification of adducts… read more here.
Keywords: lipid peroxidation; calpain activity; hne; products influence ... See more keywords
From a computational point of view: deciphering the molecular synergism between oxidative stress-induced lipid peroxidation products and metabolic dysfunctionality of human liver mitochondrial aldehyde dehydrogenase-2
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Simulation"
DOI: 10.1080/08927022.2019.1578355
Abstract: ABSTRACT Accumulation of oxidative stress-induced lipid peroxidation products; 4-hydroxynonenal (4HNE) and 4-oxononenal (4ONE), inactivates the metabolic activity of human liver aldehyde dehydrogenase 2 (ALDH2), an enzyme that converts acetaldehyde to carboxylic acids during alcohol metabolism.… read more here.
Keywords: induced lipid; lipid peroxidation; stress induced; peroxidation products ... See more keywords
Probucol induces the generation of lipid peroxidation products in erythrocytes and plasma of male cynomolgus macaques
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Biochemistry and Nutrition"
DOI: 10.3164/jcbn.18-7
Abstract: We previously reported that probucol, a lipid lowering agent, protected mice from malaria infection via depletion in plasma α-tocopherol. The antioxidant α-tocopherol in host circulation is necessary for the malaria parasites to protect themselves from… read more here.
Keywords: probucol induces; erythrocytes plasma; lipid peroxidation; peroxidation ... See more keywords
The role of lipid peroxidation products and antioxidant enzymes in the pathogenesis of aseptic and purulent inflammation in cats
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Advanced Veterinary and Animal Research"
DOI: 10.5455/javar.2021.h504
Abstract: Objective: The work aimed to determine the state of lipid peroxidation products and the activity of the antioxidant system in cats with aseptic inflammation and purulent-inflammatory processes of varying severity. Materials and Methods: The intensity… read more here.
Keywords: purulent; inflammation; lipid peroxidation; peroxidation ... See more keywords