Cholesterol transport through the peroxisome-ER membrane contacts tethered by PI(4,5)P2 and extended synaptotagmins
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DOI: 10.1007/s11427-019-9569-9
Abstract: Most mammalian cells take up cholesterol from low-density lipoproteins (LDLs) via receptor-mediated endocytosis. After reaching lysosomes, LDL-derived cholesterol continues to transport to downstream organelles including the ER for specific structural and functional needs. Peroxisomes are… read more here.
Keywords: peroxisome membrane; cholesterol transport; membrane; membrane contacts ... See more keywords
Determinants of Peroxisome Membrane Dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.834411
Abstract: Organelles within the cell are highly dynamic entities, requiring dramatic morphological changes to support their function and maintenance. As a result, organelle membranes are also highly dynamic, adapting to a range of topologies as the… read more here.
Keywords: function; membrane dynamics; peroxisome membrane; membrane ... See more keywords