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Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.155836
Abstract: Peroxisomes are specialized cellular organelles involved in a variety of metabolic processes. In humans, mutations leading to complete loss of peroxisomes cause multiorgan failure (Zellweger’s spectrum disorders, ZSD), including renal impairment. However, the (patho)physiological role…
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Keywords:
cko mice;
function;
peroxisomes dispensable;
kidney ... See more keywords