A Diazaborine Activity‐Based Sensing Fluorescent Probe Reports Endogenously Produced Mitochondrial Peroxynitrite in Live Macrophages
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DOI: 10.1002/cbic.202400972
Abstract: We present the synthesis, properties, and imaging applications of a new class of diazaborine‐based probes (Peroxynitrite Probe‐1, PNP‐1) for selective peroxynitrite (ONOO−) imaging in live cells. PNP‐1 features a diazaborine‐based reaction motif that provides excellent… read more here.
Keywords: diazaborine activity; based sensing; peroxynitrite; activity based ... See more keywords
Scavenging of lipid peroxyl radicals protects plasma lipids and proteins from peroxynitrite.
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DOI: 10.3892/br.2018.1144
Abstract: Peroxynitrite can be produced in the vasculature from a superoxide anion reaction with nitric oxide. A surplus of peroxynitrite in the intravascular compartment is a common feature of several chronic diseases. The development of pharmacological… read more here.
Keywords: peroxyl radicals; scavenging lipid; lipid peroxyl; blood plasma ... See more keywords