The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells
Sign Up to like & getrecommendations! Published in 2020 at "Immunity"
DOI: 10.1016/j.immuni.2020.12.001
Abstract: The interleukin-6 (IL-6) membrane receptor and its circulating soluble form, sIL-6R, can be targeted by antibody therapy to reduce deleterious immune signaling caused by chronic overexpression of the pro-inflammatory cytokine IL-6. This strategy may also hold… read more here.
Keywords: persistence interleukin; dendritic cells; buffer system;
Persistence of interleukin (IL)‐17A+ T lymphocytes and IL‐17A expression in treatment‐resistant psoriatic plaques despite ustekinumab therapy
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Dermatology"
DOI: 10.1111/bjd.15029
Abstract: With the widespread use of monoclonal antibodies directed against cytokines in the treatment of psoriasis, we are presented with opportunities to investigate paradigms in cutaneous immunology, notably with respect to the ongoing skin inflammation that… read more here.
Keywords: persistence interleukin; treatment; interleukin 17a; lymphocytes 17a ... See more keywords