Subthreshold basis for reward-predictive persistent activity in mouse prefrontal cortex
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109082
Abstract: SUMMARY Nervous systems maintain information internally using persistent activity changes. The mechanisms by which this activity arises are incompletely understood. We study prefrontal cortex (PFC) in mice performing behaviors in which stimuli predicted rewards at… read more here.
Keywords: predictive persistent; reward predictive; persistent activity; activity ... See more keywords
Circuit mechanisms for the maintenance and manipulation of information in working memory
Sign Up to like & getrecommendations! Published in 2019 at "Nature Neuroscience"
DOI: 10.1038/s41593-019-0414-3
Abstract: Recently it has been proposed that information in working memory (WM) may not always be stored in persistent neuronal activity but can be maintained in ‘activity-silent’ hidden states, such as synaptic efficacies endowed with short-term… read more here.
Keywords: information working; working memory; persistent activity; activity ... See more keywords
Stabilized supralinear network can give rise to bistable, oscillatory, and persistent activity
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1700080115
Abstract: Significance Many fundamental neural computations from normalization to rhythm generation emerge from the same cortical hardware, but they often require dedicated models to explain each phenomenon. Recently, the stabilized supralinear network (SSN) model has been… read more here.
Keywords: ssn model; network; stabilized supralinear; model ... See more keywords
Disparities in Short-Term Depression Among Prefrontal Cortex Synapses Sustain Persistent Activity in a Balanced Network.
Sign Up to like & getrecommendations! Published in 2019 at "Cerebral cortex"
DOI: 10.1093/cercor/bhz076
Abstract: Persistent activity of cue-representing neurons in the prefrontal cortex (PFC) is regarded as a neural basis for working memory. The contribution of short-term synaptic plasticity (STP) at different types of synapses comprising the cortical network… read more here.
Keywords: prefrontal cortex; activity; persistent activity; depression ... See more keywords
Effects of M currents on the persistent activity of pyramidal neurons in mouse primary auditory cortex.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurophysiology"
DOI: 10.1152/jn.00332.2021
Abstract: Neuronal persistent activity (PA) is a common phenomenon observed in many types of neurons. PA can be induced in neurons in the mouse auditory nucleus by activating cholinergic receptors with carbachol (CCh), a dual muscarinic… read more here.
Keywords: pyramidal neurons; persistent activity; neurons mouse; auditory cortex ... See more keywords
Recurrent circuit dynamics underlie persistent activity in the macaque frontoparietal network
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.52460
Abstract: During delayed oculomotor response tasks, neurons in the lateral intraparietal area (LIP) and the frontal eye fields (FEF) exhibit persistent activity that reflects the active maintenance of behaviorally relevant information. Despite many computational models of… read more here.
Keywords: circuit dynamics; persistent activity; frontoparietal network; activity ... See more keywords