Articles with "persistent mutations" as a keyword



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Abstract 1393: Persistent mutation burden drives sustained anti-tumor immune responses in human cancers

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-1393

Abstract: INTRODUCTION: Tumor mutation burden (TMB) is a commonly used biomarker for cancer immunotherapy however TMB only partially captures tumor foreignness. We hypothesized that mutations in single-copy regions of the genome or mutations present in multiple… read more here.

Keywords: icb; mutation burden; persistent mutations; tumor ... See more keywords