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Published in 2017 at "World Journal of Pediatrics"
DOI: 10.1007/s12519-017-0056-z
Abstract: BackgroundSeveral studies have clearly demonstrated a significantly higher incidence of persistent pulmonary hypertension of the newborn (PPHN) in neonates delivered by caesarean section (CS) compared to those delivered vaginally. The pathophysiological factors underlying the link… read more here.
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Published in 2020 at "Indian Pediatrics"
DOI: 10.1007/s13312-020-1972-x
Abstract: Persistent pulmonary hypertension of the newborn (PPHN) affects about 2/1000 newborn. The mainstay of therapy is supportive high frequency oscillatory ventilation (HFOV) and inhaled nitric oxide (NO), which have decreased the need for Extracorporeal membrane… read more here.
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Published in 2021 at "Clinics in perinatology"
DOI: 10.1016/j.clp.2021.05.009
Abstract: Persistent pulmonary hypertension of the newborn (PPHN) is a disorder of circulatory transition resulting in high pulmonary vascular resistance with extrapulmonary right-to-left shunts causing hypoxemia. There has been substantial gain in understanding of pathophysiology of… read more here.
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Published in 2022 at "Current problems in cardiology"
DOI: 10.1016/j.cpcardiol.2022.101181
Abstract: OBJECTIVE To examine echocardiographic (ECHO) parameters correlation with clinical severity indices, Alveolar- arterial gradient (A-a gradient), oxygenation index (OI) and clinical outcomes in newborns with persistent pulmonary hypertension of the newborn (PPHN). STUDY DESIGN Retrospective… read more here.
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Published in 2022 at "Cardiology in the young"
DOI: 10.1017/s1047951121005072
Abstract: OBJECTIVE To determine the efficacy and safety of endotracheal instillation of iloprost as a rescue therapy for persistent pulmonary hypertension of the newborn. METHODS Neonates diagnosed with persistent pulmonary hypertension who were unresponsive to standard… read more here.
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Published in 2021 at "Journal of Perinatology"
DOI: 10.1038/s41372-021-00962-6
Abstract: This study aims to determine the immediate outcome of persistent pulmonary hypertension of the newborn (PPHN) and risk factors for mortality in the era of inhaled nitric oxide (iNO). This observational cross-sectional study includes 195… read more here.
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Published in 2021 at "American journal of perinatology"
DOI: 10.1055/a-1711-0778
Abstract: Persistent pulmonary hypertension of the newborn, or PPHN, represents a challenging condition associated with high morbidity and mortality. Management is complicated by complex pathophysiology and limited neonatal specific evidence-based literature, leading to a lack of… read more here.
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Published in 2018 at "American Journal of Perinatology"
DOI: 10.1055/s-0037-1607213
Abstract: Abstract Objective This study aims to determine the risk factors and outcome of persistent pulmonary hypertension of the newborn (PPHN)‐associated acute kidney injury (AKI). Study Design Infants diagnosed with PPHN at Hat Yai Hospital from… read more here.
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Published in 2018 at "American Journal of Perinatology"
DOI: 10.1055/s-0038-1660462
Abstract: &NA; Persistent pulmonary hypertension of the newborn (PPHN) is a complication of several respiratory diseases characterized by an elevation in pulmonary vascular resistance with resultant right‐to‐left shunting of blood and severe hypoxemia in the neonatal… read more here.
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Published in 2019 at "American Journal of Perinatology"
DOI: 10.1055/s-0039-1692182
Abstract: Objective The aim of this study was to establish the effects of treprostinil in congenital diaphragmatic hernia (CDH) patients with persistent pulmonary hypertension (PHT) after 1 week of treatment. Drug effects were assessed by oxygenation index… read more here.
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Published in 2019 at "Anesthesiology"
DOI: 10.1097/aln.0000000000002579
Abstract: Inhaled Nitric Oxide in Persistent Pulmonary Hypertension of the Newborn. By Roberts JD, Polaner DM, Lang P, and Zapol WM. Lancet 1992; 130:435-40. Reprinted with permission.NO has vasodilatory effects on the pulmonary vasculature in adults… read more here.