How persister bacteria evade antibiotics, prolong infections
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2215617119
Abstract: When exposed to antibiotics, some elusive bacteria lie low—so low, in fact, that they’re actually inaccessible to the drugs. Researchers first identified these unique antibiotic-tolerant cells, also known as persisters, shortly after penicillin was first… read more here.
Keywords: evade antibiotics; persister bacteria; infections persister; antibiotics prolong ... See more keywords
Adenosine Awakens Metabolism to Enhance Growth-Independent Killing of Tolerant and Persister Bacteria across Multiple Classes of Antibiotics
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DOI: 10.1128/mbio.00480-22
Abstract: Antibiotic tolerance, which is a hallmark of persister bacteria, contributes to treatment-refractory infections and the emergence of heritable antimicrobial resistance. Drugs that reverse tolerance and persistence may become part of the arsenal to combat antimicrobial… read more here.
Keywords: antibiotic tolerance; growth; persister bacteria; resistance ... See more keywords