Medium chain unsaturated fatty acid ethyl esters inhibit persister formation of Escherichia coli via antitoxin HipB
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-9271-3
Abstract: Persisters represent a small bacterial population that is dormant and that survives under antibiotic treatment without experiencing genetic adaptation. Persisters are also considered one of the major reasons for recalcitrant chronic bacterial infections. Although several… read more here.
Keywords: acid ethyl; fatty acid; formation; persister formation ... See more keywords
Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection
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DOI: 10.1038/s41467-018-04472-6
Abstract: Non-typhoidal Salmonella strains are responsible for invasive infections associated with high mortality and recurrence in sub-Saharan Africa, and there is strong evidence for clonal relapse following antibiotic treatment. Persisters are non-growing bacteria that are thought… read more here.
Keywords: persister formation; acetyltransferase toxins; salmonella persister; persister ... See more keywords
Macrophage-Produced Peroxynitrite Induces Antibiotic Tolerance and Supersedes Intrinsic Mechanisms of Persister Formation
Sign Up to like & getrecommendations! Published in 2021 at "Infection and Immunity"
DOI: 10.1128/iai.00286-21
Abstract: Staphylococcus aureus is a leading human pathogen that frequently causes chronic and relapsing infections. Antibiotic-tolerant persister cells contribute to frequent antibiotic failure in patients. ABSTRACT Staphylococcus aureus is a leading human pathogen that frequently causes… read more here.
Keywords: antibiotic tolerance; induces antibiotic; persister formation; persister ... See more keywords
The Role of Integration Host Factor in Escherichia coli Persister Formation
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DOI: 10.1128/mbio.03420-21
Abstract: Persisters are phenotypic variants that survive exposure to antibiotics through temporary dormancy. Mutants with increased levels of persisters have been identified in clinical isolates, and evidence suggests these cells contribute to chronic infections and antibiotic… read more here.
Keywords: persister formation; escherichia coli; integration host; chronic infections ... See more keywords
Magnesium Links Starvation-Mediated Antibiotic Persistence to ATP
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DOI: 10.1128/msphere.00862-19
Abstract: Various genes have been identified to be involved in bacterial persister formation regardless of the presence or absence of persister genes. Despite recent discoveries of the roles of ATP and membrane potential in persister formation,… read more here.
Keywords: mg2; persistence; persister; atp ... See more keywords
The Agr Quorum Sensing System Represses Persister Formation through Regulation of Phenol Soluble Modulins in Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2017.02189
Abstract: The opportunistic pathogen Staphylococcus aureus has become an increasing threat to public health. While the Agr quorum sensing (QS) system is a master regulator of S. aureus virulence, its dysfunction has been frequently reported to… read more here.
Keywords: phenol soluble; system; agr; formation ... See more keywords
Identification of Genes Involved in Bacteriostatic Antibiotic-Induced Persister Formation
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2018.00413
Abstract: Persister cells are metabolically quiescent multi-drug tolerant fraction of a genetically sensitive bacterial population and are thought to be responsible for relapse of many persistent infections. Persisters can be formed naturally in the stationary phase… read more here.
Keywords: persister formation; induced persister; bacteriostatic antibiotic; antibiotic induced ... See more keywords