Circulating tumor DNA (ctDNA) in the era of personalized cancer therapy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Diabetes and Metabolic Disorders"
DOI: 10.1007/s40200-018-0334-x
Abstract: The heterogeneity of tumor is considered as a major difficulty to victorious personalized cancer medicine. There is an extremeneed of consistent response evaluation for in vivo tumor heterogeneity anditscoupledconflict mechanisms. In this occasion researchers will… read more here.
Keywords: medicine; personalized cancer; circulating tumor; tumor dna ... See more keywords
Enhancing therapeutic performance of personalized cancer vaccine via delivery vectors.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2021.113927
Abstract: In recent years, personalized cancer vaccines have gained increasing attention as emerging immunotherapies with the capability to overcome interindividual differences and show great benefits for individual patients in the clinic due to the highly tailored… read more here.
Keywords: delivery; therapeutic performance; personalized cancer; vaccine ... See more keywords
Recruitment of dendritic cells using 'find-me' signaling microparticles for personalized cancer immunotherapy.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121412
Abstract: Therapeutic cancer vaccines have attracted attention because of their potential to prime cytotoxic T cells, which are highly antigen (Ag)-specific, allowing personalized cancer immunotherapy. However, because of their low immunogenicity, cancer vaccines have been used… read more here.
Keywords: cancer; personalized cancer; cancer immunotherapy; find signaling ... See more keywords
Surgical Tumor-Derived Personalized Photothermal Vaccine Formulation for Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.8b07371
Abstract: Personalized cancer vaccines show great potential in cancer immunotherapy by inducing an effective and durable antitumor response. However, the limitation of neoantigen identification, low immunogenicity, and weak immune response hamper the development of personalized cancer… read more here.
Keywords: personalized photothermal; personalized cancer; cancer immunotherapy; cancer ... See more keywords
Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer
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DOI: 10.1038/s41541-021-00297-5
Abstract: T cells are important for controlling ovarian cancer (OC). We previously demonstrated that combinatorial use of a personalized whole-tumor lysate-pulsed dendritic cell vaccine (OCDC), bevacizumab (Bev), and cyclophosphamide (Cy) elicited neoantigen-specific T cells and prolonged… read more here.
Keywords: strategy; personalized cancer; cancer vaccine; ovarian cancer ... See more keywords
A simple and general strategy for postsurgical personalized cancer vaccine therapy based on an injectable dynamic covalent hydrogel.
Sign Up to like & getrecommendations! Published in 2021 at "Biomaterials science"
DOI: 10.1039/d1bm01000j
Abstract: Cancer vaccines artificially stimulate the immune system against cancer and are considered the most promising treatment of cancer. However, the current progress in vaccine research against cancer is still limited and slow, partially due to… read more here.
Keywords: covalent hydrogel; dynamic covalent; personalized cancer; cancer ... See more keywords
Personalized cancer care
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Association of Nurse Practitioners"
DOI: 10.1097/jxx.0000000000000793
Abstract: ABSTRACT The completion of the Human Genome Project in 2003 has led to the development of molecular profiling platforms that have changed the trajectory of cancer care. These technologies continue to advance, and with the… read more here.
Keywords: medicine; personalized cancer; cancer care; cancer ... See more keywords
"Personalized Cancer Therapy": A Publicly Available Precision Oncology Resource.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-17-0341
Abstract: High-throughput genomic and molecular profiling of tumors is emerging as an important clinical approach. Molecular profiling is increasingly being used to guide cancer patient care, especially in advanced and incurable cancers. However, navigating the scientific… read more here.
Keywords: resource; personalized cancer; cancer; oncology ... See more keywords
Abstract 4642: Personalized cancer-specific protein corona affects the therapeutic impact of nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4642
Abstract: Despite recent progress in nanomedicine, there is still a lack of efficient nanotherapeutics for cancer treatment. When nanoparticles (NPs) are injected, they circulate the bloodstream and interact with biomolecules, creating a biomolecular shell. This shell… read more here.
Keywords: impact; cancer specific; personalized cancer; protein corona ... See more keywords
Abstract IA04: Game theory and personalized cancer treatment
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.epso16-ia04
Abstract: The presence of driver mutations and subsequent clonal expansion by Darwinian evolution does not explain dormancy and re-emergence of cancer from a community of cancer and host cells (including stromal and immune cells). Dormancy appears… read more here.
Keywords: theory personalized; personalized cancer; game theory; cancer treatment ... See more keywords
Novel Biomarkers for Personalized Cancer Immunotherapy
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DOI: 10.3390/cancers11091223
Abstract: Cancer immunotherapy has emerged as a novel and effective treatment strategy for several types of cancer. Immune checkpoint inhibitors (ICIs) have recently demonstrated impressive clinical benefit in some advanced cancers. Nonetheless, in the majority of… read more here.
Keywords: biomarkers personalized; personalized cancer; novel biomarkers; cancer immunotherapy ... See more keywords