Identification of clinically relevant T cell receptors for personalized T cell therapy using combinatorial algorithms
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DOI: 10.1038/s41587-024-02232-0
Abstract: A central challenge in developing personalized cancer cell immunotherapy is the identification of tumor-reactive T cell receptors (TCRs). By exploiting the distinct transcriptomic profile of tumor-reactive T cells relative to bystander cells, we build and… read more here.
Keywords: clinically relevant; cell receptors; personalized cell; cell therapy ... See more keywords