Towards a More Personalized Treatment of Dyslipidemias to Prevent Cardiovascular Disease
Sign Up to like & getrecommendations! Published in 2018 at "Current Cardiology Reports"
DOI: 10.1007/s11886-018-0996-5
Abstract: Purpose of ReviewToday, statins are the first choice to lower LDL cholesterol and concomitantly the risk of atherosclerotic cardiovascular disease. There is a significant minority of statin-treated patients who are more susceptible to occasionally serious… read more here.
Keywords: dyslipidemias prevent; treatment dyslipidemias; towards personalized; personalized treatment ... See more keywords
A simple, universal and multifunctional template agent for personalized treatment of bone tumors
Sign Up to like & getrecommendations! Published in 2022 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.10.027
Abstract: Bone tumors occur in bone or its accessory tissues. Benign bone tumors are easy to cure and have good prognosis, while malignant bone tumors develop rapidly and have poor and high mortality. So far, there… read more here.
Keywords: bone; bone tumors; personalized treatment; template ... See more keywords
Probabilistic modeling personalized treatment pathways using electronic health records
Sign Up to like & getrecommendations! Published in 2018 at "Journal of biomedical informatics"
DOI: 10.1016/j.jbi.2018.08.004
Abstract: BACKGROUND Modeling personalized treatment pathways plays an important role in understanding essential/critical treatment behaviors performed on patients during their hospitalizations and thus provides the opportunity for the improvement of better health service delivery in treatment… read more here.
Keywords: treatment pathways; treatment; electronic health; personalized treatment ... See more keywords
Organ preservation in bladder cancer: an opportunity for truly personalized treatment
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Urology"
DOI: 10.1038/s41585-019-0199-x
Abstract: Radical treatment of many solid tumours has moved from surgery to multimodal organ preservation strategies combining systemic and local treatments. Trimodality bladder-preserving treatment (TMT) comprises maximal transurethral resection of the bladder tumour followed by radiotherapy… read more here.
Keywords: bladder cancer; organ preservation; bladder; treatment ... See more keywords
Deep learning in digital pathology for personalized treatment plans of cancer patients.
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in diagnostic pathology"
DOI: 10.1053/j.semdp.2023.02.003
Abstract: Over the past decade, many new cancer treatments have been developed and made available to patients. However, in most cases, these treatments only benefit a specific subgroup of patients, making the selection of treatment for… read more here.
Keywords: personalized treatment; treatment plans; pathology; treatment ... See more keywords
Personalized treatment selection using observational data
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Statistics"
DOI: 10.1080/02664763.2021.2019689
Abstract: Estimating the optimal treatment regime based on individual patient characteristics has been a topic of discussion in many forums. Advanced computational power has added momentum to this discussion over the last two decades and practitioners… read more here.
Keywords: personalized treatment; optimal treatment; observational data; treatment selection ... See more keywords
PATH-63. TRANSCRIPTIONAL SIGNATURES IN HISTOLOGIC STRUCTURES WITHIN GLIOBLASTOMA TUMORS MAY PREDICT PERSONALIZED TREATMENT SENSITIVITY AND SURVIVAL
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.658
Abstract: Personalized treatment strategies in Glioblastoma multiforme (GBM) has been hampered by intra-tumoral heterogeneity. The goals of this study were to (1) determine the impact of intra-tumoral heterogeneity on established predictive and prognostic transcriptional signatures in… read more here.
Keywords: transcriptional signatures; gbm; tumors may; personalized treatment ... See more keywords
Personalized treatment of malignant tumors during pregnancy
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029803
Abstract: The combination of pregnancy and cancer is a challenge for the patient and a problematic clinical dilemma for the doctor. In this retrospective observational cohort study, we have tried to analyze our experience in the… read more here.
Keywords: malignant tumors; personalized treatment; received treatment; treatment malignant ... See more keywords
Personalized treatment for hepatocellular carcinoma: Current status and future perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Gastroenterology and Hepatology"
DOI: 10.1111/jgh.15889
Abstract: Systemic treatment for hepatocellular carcinoma (HCC) has been advancing rapidly over the last decade. More novel agents, including both targeted agents and immune checkpoint inhibitors, are available for physicians to use sequentially or concurrently for… read more here.
Keywords: tumor heterogeneity; heterogeneity; personalized treatment; hcc ... See more keywords
Sensitive detection of single-nucleotide polymorphisms by conjugated polymers for personalized treatment of hypertension
Sign Up to like & getrecommendations! Published in 2023 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.abq5753
Abstract: Genetic variants among individuals have been associated with ineffective control of hypertension. Previous work has shown that hypertension has a polygenic nature, and interactions between these loci have been associated with variations in drug response.… read more here.
Keywords: treatment hypertension; personalized treatment; hypertension; detection ... See more keywords
Chronic GvHD NIH Consensus Project Biology Task Force: Evolving path to personalized treatment of chronic GvHD.
Sign Up to like & getrecommendations! Published in 2022 at "Blood advances"
DOI: 10.1182/bloodadvances.2022007611
Abstract: Chronic GvHD (cGvHD) remains a prominent barrier to allogeneic hematopoietic stem cell transplantion as the leading cause of non-relapse mortality and significant morbidity. Tremendous progress has been achieved in both understanding of pathophysiology and the… read more here.
Keywords: personalized treatment; biology; chronic gvhd; path ... See more keywords