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Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70459
Abstract: Evidence from clinical trials providing average effects in populations is often used to forecast individualized patient outcomes similar to the trial patients. Multiple sclerosis (MS), known for notable heterogeneity in outcomes, makes the evaluation of…
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Keywords:
treatment;
treatment response;
personalized treatment;
response progressive ... See more keywords
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Published in 2018 at "Current Cardiology Reports"
DOI: 10.1007/s11886-018-0996-5
Abstract: Purpose of ReviewToday, statins are the first choice to lower LDL cholesterol and concomitantly the risk of atherosclerotic cardiovascular disease. There is a significant minority of statin-treated patients who are more susceptible to occasionally serious…
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Keywords:
dyslipidemias prevent;
treatment dyslipidemias;
towards personalized;
personalized treatment ... See more keywords
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Published in 2025 at "Current Psychiatry Reports"
DOI: 10.1007/s11920-025-01592-x
Abstract: This paper explores Predominant Polarity (PP) in Bipolar Disorder (BD), defined as the predominance of either manic or depressive episodes over a patient’s course of illness. We examine its clinical relevance, neurobiological foundations, and potential…
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Keywords:
treatment;
personalized treatment;
polarity;
bipolar disorder ... See more keywords
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Published in 2022 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2021.10.027
Abstract: Bone tumors occur in bone or its accessory tissues. Benign bone tumors are easy to cure and have good prognosis, while malignant bone tumors develop rapidly and have poor and high mortality. So far, there…
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Keywords:
bone;
bone tumors;
personalized treatment;
template ... See more keywords
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Published in 2018 at "Journal of biomedical informatics"
DOI: 10.1016/j.jbi.2018.08.004
Abstract: BACKGROUND Modeling personalized treatment pathways plays an important role in understanding essential/critical treatment behaviors performed on patients during their hospitalizations and thus provides the opportunity for the improvement of better health service delivery in treatment…
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Keywords:
treatment pathways;
treatment;
electronic health;
personalized treatment ... See more keywords
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Published in 2019 at "Nature Reviews Urology"
DOI: 10.1038/s41585-019-0199-x
Abstract: Radical treatment of many solid tumours has moved from surgery to multimodal organ preservation strategies combining systemic and local treatments. Trimodality bladder-preserving treatment (TMT) comprises maximal transurethral resection of the bladder tumour followed by radiotherapy…
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Keywords:
bladder cancer;
organ preservation;
bladder;
treatment ... See more keywords
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Published in 2023 at "Seminars in diagnostic pathology"
DOI: 10.1053/j.semdp.2023.02.003
Abstract: Over the past decade, many new cancer treatments have been developed and made available to patients. However, in most cases, these treatments only benefit a specific subgroup of patients, making the selection of treatment for…
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Keywords:
personalized treatment;
treatment plans;
pathology;
treatment ... See more keywords
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Published in 2022 at "Journal of Applied Statistics"
DOI: 10.1080/02664763.2021.2019689
Abstract: Estimating the optimal treatment regime based on individual patient characteristics has been a topic of discussion in many forums. Advanced computational power has added momentum to this discussion over the last two decades and practitioners…
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Keywords:
personalized treatment;
optimal treatment;
observational data;
treatment selection ... See more keywords
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Published in 2025 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2025.2552784
Abstract: ABSTRACT Introduction Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by classic motor symptoms such as tremor, bradykinesia, rigidity, and postural instability as well as several non-motor symptoms. The heterogenous nature of PD has…
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Keywords:
treatment strategies;
disease;
treatment;
motor ... See more keywords
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Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.658
Abstract: Personalized treatment strategies in Glioblastoma multiforme (GBM) has been hampered by intra-tumoral heterogeneity. The goals of this study were to (1) determine the impact of intra-tumoral heterogeneity on established predictive and prognostic transcriptional signatures in…
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Keywords:
transcriptional signatures;
gbm;
tumors may;
personalized treatment ... See more keywords
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Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029803
Abstract: The combination of pregnancy and cancer is a challenge for the patient and a problematic clinical dilemma for the doctor. In this retrospective observational cohort study, we have tried to analyze our experience in the…
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Keywords:
malignant tumors;
personalized treatment;
received treatment;
treatment malignant ... See more keywords