Perspectives on the Clinical Development of NRF2-Targeting Drugs.
Sign Up to like & getrecommendations! Published in 2020 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2020_381
Abstract: The transcription factor NRF2 (nuclear factor erythroid 2-related factor 2) triggers homeostatic responses against a plethora of environmental or endogenous deviations in redox metabolism, inflammation, proteostasis, etc. Therefore, pharmacological activation of NRF2 is a promising… read more here.
Keywords: clinical development; development; factor; development nrf2 ... See more keywords
PHYSICIAN PERSPECTIVES ON CLINICAL DECISION SUPPORT FOR FAMILIAL HYPERCHOLESTEROLEMIA
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(17)35096-9
Abstract: Background: Familial hypercholesterolemia (FH) is highly prevalent but read more here.
Keywords: hypercholesterolemia; decision support; clinical decision; physician perspectives ... See more keywords
Current perspectives on the clinical management of cryptogenic stroke
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Neurotherapeutics"
DOI: 10.1080/14737175.2023.2192403
Abstract: ABSTRACT Introduction Cryptogenic stroke is a heterogeneous entity defined as an ischemic stroke for which no probable cause is identified despite thorough diagnostic evaluation. Since about a quarter of all ischemic strokes are classified as… read more here.
Keywords: perspectives clinical; cryptogenic stroke; management cryptogenic; clinical management ... See more keywords
Perspectives and clinical practices of optometrists in Saudi Arabia concerning myopia in children.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of ophthalmology"
DOI: 10.18240/ijo.2023.02.14
Abstract: AIM To investigate the practice patterns of optometrists in Saudi Arabia regarding myopia management. METHODS An internet-based survey was distributed to all practicing optometrists in Saudi Arabia (n=1886). The survey contained questions related to 1)… read more here.
Keywords: saudi arabia; perspectives clinical; myopia associated; treatment ... See more keywords
Bardet-Biedl Syndrome: Current Perspectives and Clinical Outlook
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DOI: 10.2147/tcrm.s338653
Abstract: Abstract The Bardet Biedl syndrome (BBS) is a rare inherited disorder considered a model of non-motile ciliopathy. It is in fact caused by mutations of genes encoding for proteins mainly localized to the base of… read more here.
Keywords: perspectives clinical; syndrome current; biedl syndrome; bardet biedl ... See more keywords
Current perspectives on clinical use of exosomes as novel biomarkers for cancer diagnosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.966981
Abstract: Exosomes are a heterogeneous subset of extracellular vesicles (EVs) that biogenesis from endosomes. Besides, exosomes contain a variety of molecular cargoes including proteins, lipids and nucleic acids, which play a key role in the mechanism… read more here.
Keywords: perspectives clinical; diagnosis; molecular cargoes; current perspectives ... See more keywords