Chemical Biology of H2S Signalling Through Protein Persulfidation
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.293
Abstract: Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of cysteine residues (RSH) to persulfides (RSSH), and provides a framework for understanding its physiological and pharmacological effects. Due to the inherent instability… read more here.
Keywords: chemical biology; persulfidation; protein persulfidation; biology ... See more keywords
Hydrogen Sulfide-linked Persulfidation of ABSCISIC INSENSITIVE 4 Controls Arabidopsis ABA Responses Through the Transactivation of Mitogen-Activated Protein Kinase Kinase Kinase 18.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular plant"
DOI: 10.1016/j.molp.2021.03.007
Abstract: Hydrogen sulfide (H2S) is a signaling molecule that regulates plant hormone and stress responses. The phytohormone abscisic acid (ABA) plays important role during plant adaptation to unfavorable environmental conditions and induces the persulfidation of L-CYSTEINE… read more here.
Keywords: plant; persulfidation; kinase; abi4 ... See more keywords
Hydrogen sulfide protects against spinal cord pyroptosis via persulfidation of Rac1 after lumbosacral plexus nerve injury
Sign Up to like & getrecommendations! Published in 2025 at "Cell Death Discovery"
DOI: 10.1038/s41420-025-02736-x
Abstract: Pyroptosis, a form of lytic and inflammatory programmed cell death mediated by gasdermin proteins, contributes to progressive spinal cord neurodegeneration following neural trauma. Nevertheless, the regulatory mechanisms governing this process remain inadequately characterized. In this… read more here.
Keywords: spinal cord; pyroptosis; plexus nerve; persulfidation ... See more keywords
Sulfide promotes tolerance to drought through protein persulfidation in Arabidopsis.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of experimental botany"
DOI: 10.1093/jxb/erad165
Abstract: Hydrogen sulfide (H2S) is a signaling molecule that regulates essential plant processes. In this study, the role of H2S during drought was analyzed, focused on the underlying mechanism. Pretreatments with H2S before imposing drought on… read more here.
Keywords: stress; persulfidation; drought; h2s ... See more keywords
Analysis of sulfide signaling in rice highlights specific drought responses
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erae249
Abstract: Abstract Hydrogen sulfide regulates essential plant processes, including adaptation responses to stress situations, and the best characterized mechanism of action of sulfide consists of the post-translational modification of persulfidation. In this study, we reveal the… read more here.
Keywords: rice; persulfidation; sulfide; drought responses ... See more keywords
Hydrogen Sulfide and Protein Persulfidation in Plant Stress Signaling.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of experimental botany"
DOI: 10.1093/jxb/eraf100
Abstract: Hydrogen sulfide (H2S) is increasingly recognized as a crucial signaling molecule in plants, playing key roles in regulating physiological processes and enhancing stress tolerance. This review provides an updated summary of H2S signaling in plant… read more here.
Keywords: protein persulfidation; h2s; persulfidation; plant stress ... See more keywords
Persulfidation and phosphorylation of transcription factor SlWRKY6 differentially regulate tomato fruit ripening.
Sign Up to like & getrecommendations! Published in 2024 at "Plant physiology"
DOI: 10.1093/plphys/kiae271
Abstract: Cysteine desulfhydrase (LCD) catalyzes the generation of the signaling molecule hydrogen sulfide (H2S) in plants. In this study, we found that H2S can inhibit tomato (Solanum lycopersicum) fruit ripening and SlWRKY6 undergoes differential protein persulfidation… read more here.
Keywords: fruit ripening; tomato fruit; phosphorylation; persulfidation ... See more keywords
Protein persulfidation in plants: mechanisms and functions beyond a simple stress response
Sign Up to like & getrecommendations! Published in 2024 at "Biological Chemistry"
DOI: 10.1515/hsz-2024-0038
Abstract: Abstract Posttranslational modifications (PTMs) can modulate the activity, localization and interactions of proteins and (re)define their biological function. Understanding how changing environments can alter cellular processes thus requires detailed knowledge about the dynamics of PTMs… read more here.
Keywords: protein persulfidation; mechanisms functions; persulfidation; protein ... See more keywords
Ethylene-Induced Hydrogen Sulfide Negatively Regulates Ethylene Biosynthesis by Persulfidation of ACO in Tomato Under Osmotic Stress
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2018.01517
Abstract: A number of recent studies identified hydrogen sulfide (H2S) as an important signal in plant development and adaptation to environmental stress. H2S has been proven to participate in ethylene-induced stomatal closure, but how the signaling… read more here.
Keywords: ethylene; ethylene induced; persulfidation; osmotic stress ... See more keywords
Protein Persulfidation in Plants: Function and Mechanism
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10101631
Abstract: As an endogenous gaseous transmitter, the function of hydrogen sulfide (H2S) has been extensively studied in plants. Once synthesized, H2S may be involved in almost all life processes of plants. Among them, a key route… read more here.
Keywords: persulfidation plants; mechanism; persulfidation; protein persulfidation ... See more keywords
The Combined Partial Knockdown of CBS and MPST Genes Induces Inflammation, Impairs Adipocyte Function-Related Gene Expression and Disrupts Protein Persulfidation in Human Adipocytes
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11061095
Abstract: Recent studies in mice and humans demonstrated the relevance of H2S synthesising enzymes, such as CTH, CBS, and MPST, in the physiology of adipose tissue and the differentiation of preadipocyte into adipocytes. Here, our objective… read more here.
Keywords: persulfidation; combined partial; expression; cbs ... See more keywords