Does Prolonged Weight Relief Increase the Chances of a Favourable Outcome After Containment for Perthes Disease?
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DOI: 10.1097/bpo.0000000000002302
Abstract: We have been treating children with Legg-Calvé-Perthes disease (LCPD) with a femoral varus osteotomy (PFVO) and weight relief till the disease evolves to the latter part of the stage of reconstitution (Stage IIIb). This entails… read more here.
Keywords: group; weight relief; perthes disease; stage ... See more keywords
Perspectives on the Social, Physical, and Emotional Impact of Living With Perthes’ Disease in Children and Their Family: A Mixed Methods Study
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DOI: 10.1177/2333794x19835235
Abstract: Aim. To determine the social, physical, and emotional impact of living with Perthes’ disease on affected children and their family (caregivers). Patients and Methods. Through a mixed methods approach, we interviewed 18 parents and explored… read more here.
Keywords: social physical; impact; children family; perthes disease ... See more keywords
Association of MTHFR rs1801133 and homocysteine with Legg–Calvé–Perthes disease in Mexican patients
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DOI: 10.1186/s13023-022-02264-2
Abstract: Background Legg–Calvé–Perthes disease (LCPD) is the avascular osteonecrosis of the proximal femoral epiphysis. It is a rare disease of unclear etiology in children, although alterations in coagulation or the collagen gene have been described and… read more here.
Keywords: legg calv; mthfr rs1801133; calv perthes; association ... See more keywords
Pediatric Hip Disorders: Slipped Capital Femoral Epiphysis and Legg-Calvé-Perthes Disease
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DOI: 10.1542/pir.2017-0197
Abstract: 1. Alexa J. Karkenny, MD* 2. Brandon M. Tauberg, MD* 3. Norman Y. Otsuka, MD* 1. *Montefiore Medical Center and the Children’s Hospital at Montefiore, Bronx, NY * Abbreviations: AP: : anteroposterior LCPD: : Legg-Calve-Perthes… read more here.
Keywords: perthes disease; slipped capital; legg; femoral epiphysis ... See more keywords
Microarray analysis of lncRNA and mRNA expression profiles in patients with Legg-Calve-Perthes disease
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DOI: 10.3389/fped.2022.974547
Abstract: Background The etiology and underlying pathogenic mechanisms of Legg-Calve-Perthes disease (LCPD) still remain unclear. A disruption of blood supply to the femoral head, producing ischemic necrosis, appears to be the critical pathological event. The lncRNAs… read more here.
Keywords: perthes disease; calve perthes; legg calve; lncrna mrna ... See more keywords
Molecular Biomarkers in Perthes Disease: A Review
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DOI: 10.3390/diagnostics13030471
Abstract: Background: Perthes disease is a juvenile form of osteonecrosis of the femoral head that affects children under the age of 15. One hundred years after its discovery, some light has been shed on its etiology… read more here.
Keywords: perthes disease; molecular biomarkers; disease review; factors relevant ... See more keywords
The role and underlying mechanisms of microRNA‑214 in Legg‑Calvé‑Perthes disease.
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DOI: 10.3892/mmr.2019.10271
Abstract: Legg‑Calvé‑Perthes disease (LCPD) is a pediatric form of femoral head osteonecrosis with unknown etiology. MicroRNAs (miRs) have been revealed to serve an important role in LCPD. MiR‑214 serves an important role in chondrogenesis. The aim… read more here.
Keywords: role; mir 214; legg calv; calv perthes ... See more keywords
Outcome of Closed Wedge Varus Derotation Osteotomy with Trochanteric Apophysiodesis in Perthes Disease
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DOI: 10.4103/ortho.ijortho_47_17
Abstract: Background: Perthes disease is a condition in which a self-limiting avascular event affects the capital epiphysis of the femur with a very variable course. It has been shown frequently, however, that there is a group… read more here.
Keywords: trochanteric apophysiodesis; wedge varus; apophysiodesis; perthes disease ... See more keywords