Association between the perturbation of bile acid homeostasis and valproic acid-induced hepatotoxicity.
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DOI: 10.1016/j.bcp.2019.113669
Abstract: Valproic acid (VPA), a widely prescribed antiepileptic drug, is known to induce hepatotoxicity. However, the mechanisms underlying this toxicity are not well understood. In this study, we performed a nontargeted metabolomic analysis of children with… read more here.
Keywords: vpa; acid homeostasis; hepatotoxicity; bile acid ... See more keywords