Abstract A03: Perturbation of proteostasis is lethal in SMARCB1-deficient tumors
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DOI: 10.1158/1538-7445.mousemodels17-a03
Abstract: Alterations in chromatin remodeling genes have been increasingly implicated in human oncogenesis. The SWI/SNF complex, specifically, is involved in a plethora of biologic functions including cell cycle regulation, terminal differentiation, and regulation of cell metabolism.… read more here.
Keywords: perturbation proteostasis; deficient; smarcb1 deficient; lethal smarcb1 ... See more keywords