Suppression of mucosal Th17 memory responses by acellular pertussis vaccines enhances nasal Bordetella pertussis carriage
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DOI: 10.1038/s41541-020-00270-8
Abstract: Pertussis has made a spectacular rebound in countries that have switched from whole-cell (wPV) to acellular pertussis vaccines (aPV). Here, we show that, unlike wPV, aPV, while protective against lung colonization by Bordetella pertussis (Bp),… read more here.
Keywords: memory; pertussis vaccines; acellular pertussis; bordetella pertussis ... See more keywords
The role of bactericidal and opsonic activity in immunity against Bordetella pertussis
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DOI: 10.1080/14760584.2022.2137145
Abstract: ABSTRACT Introduction Pertussis vaccines have drastically reduced the disease burden in humans since their implementation. Despite their success, pertussis remains an important global public health challenge. Bordetella pertussis resurgence could be a result of greater… read more here.
Keywords: pertussis vaccines; activity; pertussis; bordetella pertussis ... See more keywords
Novel approaches to reactivate pertussis immunity
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DOI: 10.1080/14760584.2022.2149499
Abstract: ABSTRACT Introduction Whole cell and acellular pertussis vaccines have been very effective in decreasing the deaths of neonates and infants from Bordetella pertussis. Despite high vaccine coverage worldwide, pertussis remains one of the most common… read more here.
Keywords: approaches reactivate; acellular pertussis; novel approaches; pertussis vaccines ... See more keywords
Pertussis vaccines
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DOI: 10.1097/mop.0000000000001108
Abstract: Purpose of review Pertussis is a vaccine preventable cough illness. It can be controlled by universal pertussis vaccination. Recent findings Pertussis cases and deaths in children are at a record low number. More complete use… read more here.
Keywords: pertussis vaccines; pertussis;
Erratum for Wolf et al., “Intranasal Immunization with Acellular Pertussis Vaccines Results in Long-Term Immunity to Bordetella pertussis in Mice”
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DOI: 10.1128/iai.00285-21
Abstract: Bordetella pertussis colonizes the respiratory mucosa of humans, inducing an immune response seeded in the respiratory tract. An individual, once convalescent, exhibits long-term immunity to the pathogen. Current acellular pertussis (aP) vaccines do not induce… read more here.
Keywords: immunization; immunity; term; pertussis ... See more keywords
Evaluation of Whole-Cell and Acellular Pertussis Vaccines in the Context of Long-Term Herd Immunity
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DOI: 10.3390/vaccines11010001
Abstract: After the pertussis vaccine had been introduced in the 1940s and was shown to be very successful in reducing the morbidity and mortality associated with the disease, the possibility of improving both vaccine composition and… read more here.
Keywords: cell acellular; acellular pertussis; whole cell; pertussis vaccines ... See more keywords