Modular PET Agent Construction Strategy through Strain-Promoted Double-Click Reagent with Efficient Photoclick Step.
Sign Up to like & getrecommendations! Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00427
Abstract: An efficient modular strategy for rapid assembly of positron emission tomography (PET) agents has been developed. The use of a sequential, rapid, and selective double-click reaction allows for a combinatorial approach to the cross-linking of… read more here.
Keywords: pet; pet agents; strategy; strain promoted ... See more keywords
Synthesis of 5-[18F]Fluoro-α-methyl Tryptophan: New Trp Based PET Agents
Sign Up to like & getrecommendations! Published in 2017 at "Theranostics"
DOI: 10.7150/thno.19371
Abstract: Indoleamine 2,3-dioxygenase (IDO1) plays a special role in the biology of various cancer types, because it breaks down the essential amino acid tryptophan for immune cell activation. Upregulation of IDO1 significantly correlates with the number… read more here.
Keywords: based pet; synthesis 18f; 18f fluoro; methyl tryptophan ... See more keywords