Essential Principles and Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Current medicinal chemistry"
DOI: 10.2174/0929867329666220329204054
Abstract: The translocator protein 18kDa (TSPO) is expressed in the outer mitochondrial membrane and is implicated in several functions, including cholesterol transport and stereoidogenesis. Under normal physiological conditions, TSPO is present in very low concentrations in… read more here.
Keywords: tspo pet; pet; tspo; development tspo ... See more keywords
Development of a Neurotensin-Derived 68Ga-Labeled PET Ligand with High In Vivo Stability for Imaging of NTS1 Receptor-Expressing Tumors
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DOI: 10.3390/cancers14194922
Abstract: Simple Summary Cancer diagnostics based on molecular imaging techniques such as positron emission tomography (PET) requires radiolabeled tracers, which are taken up by tumors. As the neurotensin receptor type 1 (NTS1R) is present in certain… read more here.
Keywords: pet ligand; pet; pet ligands; stability ... See more keywords
Imaging of Tauopathies with PET Ligands: State of the Art and Future Outlook
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DOI: 10.3390/diagnostics13101682
Abstract: (1) Background: Tauopathies are a group of diseases characterized by the deposition of abnormal tau protein. They are distinguished into 3R, 4R, and 3R/4R tauopathies and also include Alzheimer’s disease (AD) and chronic traumatic encephalopathy… read more here.
Keywords: imaging tauopathies; state art; ligands state; pet ligands ... See more keywords