Design, Synthesis, and Preliminary Evaluation of [68Ga]Ga-NOTA-Insulin as a PET Probe in an Alzheimer’s Disease Mouse Model
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DOI: 10.1021/acs.bioconjchem.2c00126
Abstract: Aberrant insulin signaling has been considered one of the risk factors for the development of Alzheimer’s disease (AD) and has drawn considerable attention from the research community to further study its role in AD pathophysiology.… read more here.
Keywords: brain; 68ga nota; pet probe; nota insulin ... See more keywords
Development of an FAP-Targeted PET Probe Based on a Novel Quinolinium Molecular Scaffold.
Sign Up to like & getrecommendations! Published in 2024 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.4c00214
Abstract: Fibroblast activation protein (FAP) has recently gained significant attention as a promising tumor biomarker for both diagnosis and therapeutic applications. A series of radiopharmaceuticals based on fibroblast activation protein inhibitors (FAPIs) have been developed and… read more here.
Keywords: development fap; smic 3002; quinolinium; pet probe ... See more keywords