Formation of phosphatidylethanol from endogenous phosphatidylcholines in animal tissues from pig, calf, and goat.
Sign Up to like & getrecommendations! Published in 2018 at "Forensic science international"
DOI: 10.1016/j.forsciint.2017.12.030
Abstract: In the presence of alcohol, phosphatidylcholine (PC) is transformed to the direct alcohol biomarker phosphatidylethanol (PEth). This reaction is catalyzed by the enzyme phospholipase D (PLD) and dependent on substrate availability. As recent methods have… read more here.
Keywords: peth; tissue; formation; pig calf ... See more keywords
Providing context for phosphatidylethanol as a biomarker of alcohol consumption with a pharmacokinetic model
Sign Up to like & getrecommendations! Published in 2018 at "Regulatory Toxicology and Pharmacology"
DOI: 10.1016/j.yrtph.2018.01.029
Abstract: ABSTRACT Phosphatidylethanol (PEth) is increasingly used as a biomarker of heavy drinking. Many different forms of PEth can form in red blood cell membranes from the action of the enzyme phospholipase D. PEth has a… read more here.
Keywords: alcohol consumption; pharmacokinetic model; biomarker; peth ... See more keywords
Can PEth be Detected with a Cutoff of 20 ng/mL after Single Alcohol Consumption?
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DOI: 10.1093/jat/bkac069
Abstract: Phosphatidylethanol (PEth) can be determined in capillary blood collected as dried blood spots (DBS) and is a promising direct alcohol biomarker for determination of drinking habits. Its use for abstinence monitoring needs to be evaluated.… read more here.
Keywords: cutoff single; detected cutoff; peth; alcohol ... See more keywords
Increase of PEth after single consumption of alcohol and evaluation of a volumetric DBS filter paper device.
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DOI: 10.1093/jat/bkad009
Abstract: Direct alcohol biomarkers are of growing interest for the assessment of alcohol consumption, with particular interest in phosphatidylethanol (PEth) in recent years. PEth is only formed when alcohol is present in the body. However, there… read more here.
Keywords: consumption; peth concentrations; peth; alcohol ... See more keywords