Genetic defects in peroxisome morphogenesis (Pex11β, dynamin‐like protein 1, and nucleoside diphosphate kinase 3) affect docosahexaenoic acid‐phospholipid metabolism
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DOI: 10.1002/jimd.12582
Abstract: Peroxisomes are essential organelles involved in lipid metabolisms including plasmalogen biosynthesis and β‐oxidation of very long‐chain fatty acids. Peroxisomes proliferate by the growth and division of pre‐existing peroxisomes. The peroxisomal membrane is elongated by Pex11β… read more here.
Keywords: docosahexaenoic acid; pex11; nucleoside diphosphate; acid ... See more keywords
PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor
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DOI: 10.1242/jcs.259924
Abstract: ABSTRACT Peroxisome membrane dynamics and division are essential to adapt the peroxisomal compartment to cellular needs. The peroxisomal membrane protein PEX11β (also known as PEX11B) and the tail-anchored adaptor proteins FIS1 (mitochondrial fission protein 1)… read more here.
Keywords: mitochondrial fission; pex11; peroxisome division; fission factor ... See more keywords
A Novel Mutation in PEX11β Gene
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DOI: 10.22037/ijcn.v15i1.26129
Abstract: PEX11β ([OMIM] 614920) mutation causes an extremely rare subgroup of peroxisomal biogenesis disorders, with only six cases reported to date. In this article, we reported a patient with episodic migraine-like attacks, delirium, mood and behavior… read more here.
Keywords: pex11 gene; pex11; novel mutation; mutation pex11 ... See more keywords