The sorting nexin FgAtg20 is involved in the Cvt pathway, nonâselective macroautophagy, pexophagy and pathogenesis in Fusarium graminearum
Sign Up to like & getrecommendations! Published in 2020 at "Cellular Microbiology"
DOI: 10.1111/cmi.13208
Abstract: The sorting nexin Atg20/Snx42 plays an important role in autophagy. The wheat head blight pathogen Fusarium graminearum contains an FgAtg20 protein orthologous to Saccharomyces cerevisiae Atg20/Snx42, but its function remains largely unknown. Here, we report… read more here.
Keywords: pexophagy; non selective; selective macroautophagy; cvt pathway ... See more keywords
Mammalian pexophagy at a glance
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DOI: 10.1242/jcs.259775
Abstract: ABSTRACT Peroxisomes are highly plastic organelles that are involved in several metabolic processes, including fatty acid oxidation, ether lipid synthesis and redox homeostasis. Their abundance and activity are dynamically regulated in response to nutrient availability… read more here.
Keywords: pexophagy; mammalian pexophagy; pexophagy glance;
Enhanced Levels of Peroxisome-Derived H2O2 Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells
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DOI: 10.3390/antiox12030613
Abstract: Peroxisomes are functionally specialized organelles that harbor multiple hydrogen peroxide (H2O2)-producing and -degrading enzymes. Given that this oxidant functions as a major redox signaling agent, peroxisomes have the intrinsic ability to mediate and modulate H2O2-driven… read more here.
Keywords: autophagic flux; h2o2; impair autophagic; hek 293 ... See more keywords
The peroxisomal exportomer directly inhibits phosphoactivation of the pexophagy receptor Atg36 to suppress pexophagy in yeast
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DOI: 10.7554/elife.74531
Abstract: Autophagy receptor (or adaptor) proteins facilitate lysosomal destruction of various organelles in response to cellular stress, including nutrient deprivation. To what extent membrane-resident autophagy receptors also respond to organelle-restricted cues to induce selective autophagy remains… read more here.
Keywords: receptor atg36; atg36; yeast; pexophagy receptor ... See more keywords