The sorting nexin FgAtg20 is involved in the Cvt pathway, nonâselective macroautophagy, pexophagy and pathogenesis in Fusarium graminearum
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DOI: 10.1111/cmi.13208
Abstract: The sorting nexin Atg20/Snx42 plays an important role in autophagy. The wheat head blight pathogen Fusarium graminearum contains an FgAtg20 protein orthologous to Saccharomyces cerevisiae Atg20/Snx42, but its function remains largely unknown. Here, we report… read more here.
Keywords: pexophagy; non selective; selective macroautophagy; cvt pathway ... See more keywords
Enhanced Levels of Peroxisome-Derived H2O2 Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells
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DOI: 10.3390/antiox12030613
Abstract: Peroxisomes are functionally specialized organelles that harbor multiple hydrogen peroxide (H2O2)-producing and -degrading enzymes. Given that this oxidant functions as a major redox signaling agent, peroxisomes have the intrinsic ability to mediate and modulate H2O2-driven… read more here.
Keywords: autophagic flux; h2o2; impair autophagic; hek 293 ... See more keywords
The peroxisomal exportomer directly inhibits phosphoactivation of the pexophagy receptor Atg36 to suppress pexophagy in yeast
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DOI: 10.7554/elife.74531
Abstract: Autophagy receptor (or adaptor) proteins facilitate lysosomal destruction of various organelles in response to cellular stress, including nutrient deprivation. To what extent membrane-resident autophagy receptors also respond to organelle-restricted cues to induce selective autophagy remains… read more here.
Keywords: receptor atg36; atg36; yeast; pexophagy receptor ... See more keywords