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Published in 2017 at "Nature Immunology"
DOI: 10.1038/ni.3786
Abstract: Pneumonia is caused by pathobionts present in the respiratory tract, such as Streptococcus pneumoniae. In Mucosal Immunology, Mizgerd and colleagues show that resistance to pneumonia is provided by highly localized resident memory T cells (TRM…
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Keywords:
protection;
peyer patches;
immunology;
trm cells ... See more keywords
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Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-69632-5
Abstract: Interleukin-2 (IL-2) has both pro- and anti-inflammatory properties that have been harnessed clinically and that are used experimentally to modulate leukocyte subsets in vivo. In mice, the bioavailability and half-life of IL-2 in vivo can…
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Keywords:
signals cause;
targetted signals;
acute selective;
cd122 targetted ... See more keywords
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Published in 2020 at "Experimental Biology and Medicine"
DOI: 10.1177/1535370220973014
Abstract: Peyer’s patches are gut-associated lymphoid tissue located throughout the intestinal wall. Peyer’s patches consist of highly organized ovoid-shaped follicles, classified as non-encapsulated lymphatic tissues, populated with B cells, T cells, macrophages, and dendritic cells and…
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Keywords:
transcriptome analysis;
whole transcriptome;
regional heterogeneity;
peyer ... See more keywords
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Published in 2021 at "Microbiome"
DOI: 10.1186/s40168-021-01128-4
Abstract: Background Intestinal Peyer’s patches (PPs) form unique niches for bacteria-immune cell interactions that direct host immunity and shape the microbiome. Here we investigate how peroral administration of probiotic bacterium Limosilactobacillus reuteri R2LC affects B lymphocytes…
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Keywords:
peyer patches;
cell subsets;
distinct cell;
subsets peyer ... See more keywords
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Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02345
Abstract: Microfold (M) cells are located in the epithelium covering mucosa-associated lymphoid tissues, such as the Peyer's patches (PPs) of the small intestine. M cells actively transport luminal antigens to the underlying lymphoid follicles to initiate…
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Keywords:
microfold cells;
autoimmune;
autoimmune diseases;
immune system ... See more keywords
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Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.604674
Abstract: Morphogenesis and differentiation of organs is required for subsequent functional maturation. The morphological features of Peyer's patches vary among species. In pigs, they develop extensively in the ileum as ileal Peyer's patches (IPPs). However, the…
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Keywords:
initiated prenatally;
peyer patches;
organogenesis;
ileal peyer ... See more keywords
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Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.761949
Abstract: The decline in mucosal immunity during aging increases susceptibility, morbidity and mortality to infections acquired via the gastrointestinal and respiratory tracts in the elderly. We previously showed that this immunosenescence includes a reduction in the…
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Keywords:
aged mice;
paneth cells;
peyer patches;
aging related ... See more keywords
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Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.889552
Abstract: The proinflammatory cytokine tumor necrosis factor (TNF) has been described as one of the main mediators of intestinal inflammatory diseases, affecting the composition of tight junction (TJ) proteins and leading to a disruption of the…
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Keywords:
necrosis factor;
peyer;
peyer patches;
tumor necrosis ... See more keywords
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Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1084332
Abstract: The gastrointestinal tract contains a complex microbial community. Peyer’s patches (PPs) play an important role in inducing mucosal immune responses in the gastrointestinal tract. However, little is known about the effect of commensal microbiota on…
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Keywords:
commensal microbiota;
characteristics gene;
peyer patches;
expression ... See more keywords
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Published in 2022 at "Wiadomosci lekarskie"
DOI: 10.36740/wlek202205214
Abstract: OBJECTIVE The aim: Based on the above cytological signs of M-cells, we set the goal of more detailed clarification of some of their topological relationships with other enterocytes in the follicle-associated epithelium of Peyer's patches…
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Keywords:
small intestine;
issue;
rat small;
peyer patches ... See more keywords
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Published in 2023 at "PeerJ"
DOI: 10.7717/peerj.14647
Abstract: Bactrian camels have specific mucosa-associated lymphoid tissue (MALT) throughout the large intestine, with species-unique cystic Peyer’s patches (PPS) as the main type of tissue. However, detailed information about the molecular characteristics of PPS remains unclear.…
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Keywords:
cystic peyer;
peyer patches;
analysis;
bactrian camels ... See more keywords