Platelet-activating anti-PF4 disorders: An overview.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in hematology"
DOI: 10.1053/j.seminhematol.2022.02.005
Abstract: Platelet factor 4 (PF4) is a highly cationic tetrameric protein that can be targeted by platelet-activating anti-PF4 antibodies of immunoglobulin G (IgG) class. Certain features of PF4, including its multivalent nature (duplicate antigen sites per… read more here.
Keywords: platelet activating; pf4 disorders; pf4; activating anti ... See more keywords
Cellular contributions to the pathogenesis of anti-platelet factor 4 disorders.
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DOI: 10.1097/moh.0000000000000900
Abstract: PURPOSE OF REVIEW Anti-platelet factor 4 (PF4) disorders, including heparin-induced thrombocytopenia (HIT) and vaccine-induced immune thrombocytopenia and thrombosis (VITT), and emerging disorders such as VITT-like monoclonal gammopathy of thrombotic significance (MGTS), are monoclonal antibody-mediated and… read more here.
Keywords: pf4 disorders; factor; pathogenesis anti; platelet factor ... See more keywords