Sustained NMDA receptor hypofunction impairs brain-derived neurotropic factor signalling in the PFC, but not in the hippocampus, and disturbs PFC-dependent cognition in mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Psychopharmacology"
DOI: 10.1177/02698811211008560
Abstract: Background: Cognitive deficits profoundly impact on the quality of life of patients with schizophrenia. Alterations in brain derived neurotrophic factor (BDNF) signalling, which regulates synaptic function through the activation of full-length tropomyosin-related kinase B receptors… read more here.
Keywords: hypofunction; hippocampus; pfc; bdnf signalling ... See more keywords
EXPRESS: Evaluation of the Transient Hypofrontality Theory in the Context of Exercise: A Systematic Review with Meta-Analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Quarterly journal of experimental psychology"
DOI: 10.1177/17470218211048807
Abstract: Accumulating research suggests that, as a result of reduced neural activity in the prefrontal cortex (PFC), higher-order cognitive function may be compromised while engaging in high-intensity acute exercise, with this phenomenon referred to as the… read more here.
Keywords: exercise; transient hypofrontality; pfc dependent; acute exercise ... See more keywords