Polygenic risk score for schizophrenia and structural brain connectivity in older age: A longitudinal connectome and tractography study
Sign Up to like & getrecommendations! Published in 2018 at "Neuroimage"
DOI: 10.1016/j.neuroimage.2018.08.075
Abstract: &NA; Higher polygenic risk score for schizophrenia (szPGRS) has been associated with lower cognitive function and might be a predictor of decline in brain structure in apparently healthy populations. Age‐related declines in structural brain connectivity—measured… read more here.
Keywords: age; pfdr; brain; brain connectivity ... See more keywords
O6.4. ASSOCIATION BETWEEN CLUSTERS OF FORMAL THOUGHT DISORDERS SEVERITY AND NEUROCOGNITIVE AND FUNCTIONAL OUTCOME INDICES IN THE EARLY STAGES OF PSYCHOSIS – RESULTS FROM THE PRONIA COHORT
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbaa028.033
Abstract: Abstract Background Formal thought disorder (FThD) has been associated with more severe illness courses and functional deficits in psychosis patients. Given these associations, it remains unclear whether the presence of FThD accounts for the heterogeneous… read more here.
Keywords: package; pfdr; fthd; pfdr 0001 ... See more keywords
Causal relationships between gut microbiota and programmed cell death protein 1/programmed cell death-ligand 1: A bidirectional Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1136169
Abstract: Background Multiple clinical studies have indicated that the gut microbiota influences the effects of immune checkpoint blockade (ICB) therapy comprising PD-1/PD-L1 inhibitors, but the causal relationship is unclear. Because of numerous confounders, many microbes related… read more here.
Keywords: ivw pfdr; cell death; microbiota; programmed cell ... See more keywords
Modulations of static and dynamic functional connectivity among brain networks by electroacupuncture in post-stroke aphasia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.956931
Abstract: Introduction Post-stroke aphasia (PSA) is a language disorder caused by left hemisphere stroke. Electroacupuncture (EA) is a minimally invasive therapeutic option for PSA treatment. Tongli (HT5) and Xuanzhong (GB39), two important language-associated acupoints, are frequently… read more here.
Keywords: network; stroke aphasia; gyrus; functional connectivity ... See more keywords
Breathomics profiling of metabolic pathways affected by major depression: Possibilities and limitations
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.1061326
Abstract: Background Major depressive disorder (MDD) is one of the most common psychiatric disorders with multifactorial etiologies. Metabolomics has recently emerged as a particularly potential quantitative tool that provides a multi-parametric signature specific to several mechanisms… read more here.
Keywords: breathomics profiling; patients mdd; analysis; possibilities limitations ... See more keywords
Adverse childhood experiences and fronto-subcortical structures in the developing brain
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.955871
Abstract: The impact of adverse childhood experiences (ACEs) differs between individuals and depends on the type and timing of the ACE. The aim of this study was to assess the relation between various recently occurred ACEs… read more here.
Keywords: adverse childhood; developing brain; family; childhood experiences ... See more keywords
Urine Phthalate Levels and Liver Function in US Adolescents: Analyses of NHANES 2007–2016
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2022.843971
Abstract: Background Phthalates are non-persistent chemicals with endocrine-disrupting abilities widely used in a variety of consumer products. Evidence for the effects of phthalate exposure on liver function in adolescents is lacking. Methods Data were analyzed from… read more here.
Keywords: function; phthalate; liver function; function adolescents ... See more keywords
Integrating Common Risk Factors with Polygenic Scores Improves the Prediction of Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24020984
Abstract: We tested associations between 13 established genetic variants and type 2 diabetes (T2D) in 1371 study participants from the Volga-Ural region of the Eurasian continent, and evaluated the predictive ability of the model containing polygenic… read more here.
Keywords: polygenic scores; risk factors; type diabetes; model ... See more keywords