Plasmodium falciparum histidine-rich protein (PfHRP2 and 3) diversity in Western and Coastal Kenya
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DOI: 10.1038/s41598-018-38175-1
Abstract: Plasmodium falciparum histidine-rich proteins 2 (PfHRP2) based RDTs are advocated in falciparum malaria-endemic regions, particularly when quality microscopy is not available. However, diversity and any deletion in the pfhrp2 and pfhrp3 genes can affect the… read more here.
Keywords: pfhrp3; amino acid; pfhrp2 pfhrp3; plasmodium falciparum ... See more keywords
Genomic Deletion of PfHRP2 and PfHRP3 in Plasmodium falciparum Strains, Ethiopia, 2009
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DOI: 10.3201/eid3107.241676
Abstract: Plasmodium falciparum strains lacking P. falciparum histidine-rich protein 2 (PfHRP2) and PfHRP3 threaten malaria rapid test reliability. We show that pfhrp2/pfhrp3–deleted parasites circulated in Ethiopia as early as 2009, before widespread PfHRP2-based rapid test use,… read more here.
Keywords: plasmodium falciparum; falciparum strains; pfhrp3; pfhrp2 pfhrp3 ... See more keywords