Perfluorohexadecanoic acid increases paracellular permeability in endothelial cells through the activation of plasma kallikrein-kinin system.
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DOI: 10.1016/j.chemosphere.2017.10.002
Abstract: Per- and polyfluoroalkyl substances (PFASs) are ubiquitous and high persistent in human blood, thus potentially inducing a myriad of deleterious consequences. Plasma kallikrein-kinin system (KKS), which physiologically regulates vascular permeability, is vulnerable to exogenous stimulators,… read more here.
Keywords: permeability; endothelial cells; activation; pfhxda ... See more keywords