The Pfizer Crystal Structure Database: An essential tool for structure‐based design at Pfizer
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DOI: 10.1002/jcc.26862
Abstract: Pfizer's Crystal Structure Database (CSDB) is a key enabling technology that allows scientists on structure‐based projects rapid access to Pfizer's vast library of in‐house crystal structures, as well as a significant number of structures imported… read more here.
Keywords: structure database; structure; pfizer; pfizer crystal ... See more keywords
COVID-19 Vaccine-Associated Subclinical Axillary Lymphadenopathy on Screening Mammogram
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DOI: 10.1016/j.acra.2021.11.010
Abstract: Background Women who received a COVID-19 vaccination may display subclinical unilateral axillary lymphadenopathy on screening mammography, which can appear suspicious for malignancy, leading to additional diagnostic evaluation. Purpose To evaluate the prevalence of subclinical unilateral… read more here.
Keywords: pfizer; women received; axillary lymphadenopathy; vaccine ... See more keywords
Bullous pemphigoid after second dose of mRNA- (Pfizer-BioNTech) Covid-19 vaccine: A case report
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2022.103420
Abstract: Introduction and importance: Messenger RNA vaccines, commonly known as mRNA vaccines, are the first COVID-19 vaccines that have been authorized and licensed in the United States. Two mRNA vaccines, BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) are… read more here.
Keywords: covid vaccine; case; bullous pemphigoid; pfizer ... See more keywords
A case of Guillain–Barre syndrome following Pfizer COVID-19 vaccine
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Community Hospital Internal Medicine Perspectives"
DOI: 10.1080/20009666.2021.1954284
Abstract: ABSTRACT Since the first-reported case of Severe Acute Respiratory Distress Syndrome-Coronavirus 2 in December 2019, COVID-19 has caused a global pandemic associated with significant morbidity and mortality. After a year of advances in vaccine research… read more here.
Keywords: pfizer; covid vaccine; case; case guillain ... See more keywords
Updated efficacy and safety of entrectinib in patients with NTRK fusion-positive tumors: Integrated analysis of STARTRK-2, STARTRK-1 and ALKA-372-001
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DOI: 10.1093/annonc/mdz244.038
Abstract: Abstract Background Entrectinib is a systemic and CNS-active, potent inhibitor of TRKA/B/C and ROS1. Primary data from integrated efficacy and safety analyses (6 months’ follow-up) from entrectinib clinical trials have shown that entrectinib is a… read more here.
Keywords: research; pfizer; safety; advisory consultancy ... See more keywords
SUNitinib with EVOfosfamide (TH-302) for G1/G2 metastatic pancreatic neuroendocrine tumours (pNETs) naïve for systemic treatment. The SUNEVO phase II trial of the Spanish task force group for neuroendocrine and endocrine tumours (GETNE)
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz256.004
Abstract: Abstract Background Sunitinib (SUN) is approved for the treatment of advanced progressive pNETs. Hypoxia induced by SUN could foster the activation of the prodrug evofosfamide (EVO), designed to release the DNA alkylator bromo-isophosphoramide mustard under… read more here.
Keywords: trial; pfizer ipsen; pfizer; accommodation expenses ... See more keywords
Differences in multikinase inhibitors (MKI) toxicity profile according to gender. A pooled analysis of three phase II trials with lenvatinib, pazopanib and sorafenib in patients (pts) with advanced gastroenteropancreatic (GEP) neuroendocrine tumours (NETs)
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz256.007
Abstract: Abstract Background There is a dearth of understanding of gender influence in targeted therapies toxicity. Increasing evidence suggests a possible different toxicity profile according to gender, but mostly retrospective studies in common tumors. Currently, data… read more here.
Keywords: pfizer; according gender; toxicity; novartis ... See more keywords
1236. Safety and Immunogenicity of a 20-Valent Pneumococcal Conjugate Vaccine (PCV20) in Healthy Infants in the United States
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DOI: 10.1093/ofid/ofaa439.1421
Abstract: A 20-valent pneumococcal conjugate vaccine (PCV20) is being developed to extend protection against pneumococcal disease beyond that of the 13-valent pneumococcal vaccine (PCV13). This is the first safety and immunogenicity study of PCV20 in healthy… read more here.
Keywords: research; pfizer; pcv20; pfizer employee ... See more keywords
1580. In Vitro Activity of Ceftazidime-Avibactam Against Enterobacterales and Pseudomonas aeruginosa Collected in Latin America as part of the ATLAS Global Surveillance Program, 2017-2019
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DOI: 10.1093/ofid/ofaa439.1760
Abstract: Ceftazidime-avibactam (CAZ-AVI) is a β-lactam/non-β-lactam β-lactamase inhibitor combination with in vitro activity against Enterobacterales (Ent) and Pseudomonas aeruginosa (Psa) carrying Class A, C and some Class D β-lactamases. We examined the in vitro activity of… read more here.
Keywords: caz avi; pfizer; employee; vitro activity ... See more keywords
1604. Cost-Effectiveness of Ceftazidime-Avibactam for Patients with Hospital-Acquired Pneumonia Caused by Multi-Drug Resistant Enterobacteriaceae or Pseudomonas in China
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DOI: 10.1093/ofid/ofaa439.1784
Abstract: To estimate the cost-effectiveness of ceftazidime-avibactam (CAZ-AVI) for the treatment of hospital-acquired pneumonia (HAP) including ventilator-associated pneumonia (VAP) caused by multi-drug resistant enterobacteriaceae (MDRE) or MDR pseudomonas aeruginosa (MDRPA) in China. A previously published patient-level… read more here.
Keywords: caz avi; effectiveness ceftazidime; pfizer; cost ... See more keywords
1353. Incidence of Lyme Borreliosis in Germany: Exploring Observed Trends Over Time Using Public Surveillance Data, 2016–2020.
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DOI: 10.1093/ofid/ofac492.1182
Abstract: Abstract Background Lyme borreliosis (LB) is an infectious, vector-borne disease caused by the spirochete Borrelia burgdorferi sensu lato and mainly transmitted by the Ixodes species ticks. Public surveillance of LB occurs in 9 of 16… read more here.
Keywords: stocks bonds; incidence; 000 person; pfizer ... See more keywords