Articles with "pfk13" as a keyword



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Molecular Surveillance of Artemisinin-Based Combination Therapies Resistance in Plasmodium falciparum Parasites from Bioko Island, Equatorial Guinea

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Published in 2022 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.00413-22

Abstract: Malaria, one of the tropical parasitic diseases with a high transmission rate in Bioko Island, Equatorial Guinea, especially caused by P. falciparum is highly prevalent in this region and is commonly treated locally with ACTs.… read more here.

Keywords: pfk13; equatorial guinea; artemisinin; artemisinin based ... See more keywords
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Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

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Published in 2020 at "eLife"

DOI: 10.7554/elife.51015

Abstract: Antimalarial drug resistance has historically arisen through convergent de novo mutations in Plasmodium falciparum parasite populations in Southeast Asia and South America. For the past decade in Southeast Asia, artemisinins, the core component of first-line… read more here.

Keywords: c580y; artemisinin resistance; plasmodium falciparum; resistance ... See more keywords