PFKFB2 inhibits ferroptosis in myocardial ischemia/reperfusion injury through AMPK activation.
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DOI: 10.1097/fjc.0000000000001437
Abstract: ABSTRACT 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 (PFKFB2) is a key regulator of glycolytic enzyme. This study identified if PFKFB2 can regulate myocardial ferroptosis in ischemia/reperfusion (I/R) injury. Mice myocardial (I/R) injury and H9c2 cells oxygen-glucose deprivation/reperfusion (OGD/R)… read more here.
Keywords: reperfusion injury; pfkfb2; reperfusion; pfkfb2 inhibits ... See more keywords