The metabolic role of PFKFB4 in androgen-independent growth in vitro and PFKFB4 expression in human prostate cancer tissue
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DOI: 10.1186/s12894-020-00635-0
Abstract: Background It is well known that androgen-deprivation therapy (ADT) can inevitably drive prostate cancer (PCa) cells into a castration-resistant state. According to the “Warburg effect”, the metabolism of aggressive tumor cells increases significantly. The growth… read more here.
Keywords: lncap cells; pfkfb4 expression; tissue; pfkfb4 ... See more keywords
Effect of PFKFB4 on the Prognosis and Immune Regulation of NSCLC and Its Mechanism
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DOI: 10.2147/ijgm.s369126
Abstract: Background NSCLC (non-small cell lung cancer) has become the malignancy with the highest incidence and mortality rate worldwide. Fructose-6-phosphate 2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) is a key regulator of glycolysis with both kinase and phosphatase activities. The… read more here.
Keywords: cell; prognosis; pfkfb4 expression; pfkfb4 ... See more keywords