Articles with "pfmdr1 gene" as a keyword



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Molecular investigation of the Pfmdr1 gene of Plasmodium falciparum isolates in Henan Province imported from Africa

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Published in 2018 at "Parasitology"

DOI: 10.1017/s0031182018001609

Abstract: Abstract Efficacious antimalarial drugs are important for malaria control and elimination, and continuous monitoring of their efficacy is essential. The prevalence and distribution of Pfmdr1 were evaluated in African migrant workers in Henan Province. Among… read more here.

Keywords: molecular investigation; henan province; province; pfmdr1 gene ... See more keywords
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Selective sweeps and genetic lineages of Plasmodium falciparum multi-drug resistance (pfmdr1) gene in Kenya

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Published in 2018 at "Malaria Journal"

DOI: 10.1186/s12936-018-2534-8

Abstract: BackgroundThere are concerns that resistance to artemisinin-based combination therapy might emerge in Kenya and sub-Saharan Africa (SSA) in the same pattern as was with chloroquine and sulfadoxine–pyrimethamine. Single nucleotide polymorphisms (SNPs) in critical alleles of… read more here.

Keywords: drug resistance; genetic lineages; pfmdr1 gene; resistance ... See more keywords