Plasmodium Parasite Malate-Quinone Oxidoreductase Functionally Complements a Yeast Deletion Mutant of Mitochondrial Malate Dehydrogenase
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DOI: 10.1128/spectrum.00168-23
Abstract: We constructed a model organism to study the physiological role and function of P. falciparum malate-quinone oxidoreductase (PfMQO) in a yeast expression system. PfMQO is actively expressed in yeast mitochondria and functions in place of… read more here.
Keywords: malate quinone; mitochondrial malate; malate dehydrogenase; quinone oxidoreductase ... See more keywords
Nornidulin, A New Inhibitor of Plasmodium falciparum Malate: Quinone Oxidoreductase (PfMQO) from Indonesian Aspergillus sp. BioMCC f.T.8501
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DOI: 10.3390/ph16020268
Abstract: This study aimed to obtain a microbial active compound as a novel antimalarial drug from Indonesian isolates. Target-based assays were used to screen for antimalarial activity against the parasite mitochondrial, Plasmodium falciparum malate:quinone oxidoreductase (PfMQO)… read more here.
Keywords: plasmodium falciparum; pfmqo; falciparum malate; biomcc 8501 ... See more keywords