Long non-coding RNA TUG1 regulates the progression and metastasis of osteosarcoma cells via miR-140-5p/PFN2 axis.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201911_19541
Abstract: OBJECTIVE Osteosarcoma (OS) is a frequently occurred tumor. Recently, increasing reports disclosed that long non-coding RNA taurine upregulated gene 1 (TUG1) was associated with OS development. Nevertheless, the precise regulatory pattern was not completely understood.… read more here.
Keywords: tug1; pfn2; long non; non coding ... See more keywords
Profilin 2 Promotes Proliferation and Metastasis of Head and Neck Cancer Cells by Regulating PI3K/AKT/Ī²-Catenin Signaling Pathway
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Research"
DOI: 10.3727/096504019x15579146061957
Abstract: Profilin 2 (PFN2) was found to be mainly expressed in neurons and involved in the development of the brain. In recent years, emerging evidence indicated that PFN2 is also significantly upregulated in various cancers including… read more here.
Keywords: catenin; pfn2; neck cancer; hnsc ... See more keywords
MicroRNA-30a-5p suppresses epithelial-mesenchymal transition by targeting profilin-2 in high invasive non-small cell lung cancer cell lines.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology reports"
DOI: 10.3892/or.2017.5566
Abstract: PFN2 is an invasion promoter in several cancers including lung cancer. However, the probable effects and underlying mechanisms of PFN2 in tumor cell epithelial-mesenchymal-transition (EMT) of non-small cell lung cancerĀ (NSCLC) remain poorly understood. The protein… read more here.
Keywords: pfn2; invasion; cell lines; lung cancer ... See more keywords