Early-life perfluorooctanoic acid exposure induces obesity in male offspring and the intervention role of chlorogenic acid.
Sign Up to like & getrecommendations! Published in 2020 at "Environmental pollution"
DOI: 10.1016/j.envpol.2020.115974
Abstract: Perfluorooctanoic acid (PFOA) is an emerging organic pollutant (EOP) hazardous to human health. Effects of maternal PFOA exposure on offspring as well as the underlying mechanisms remain unclear. In this study, ICR mouse models of… read more here.
Keywords: perfluorooctanoic acid; pfoa exposure; exposure; male offspring ... See more keywords
P-353 Perfluorooctanoic acid (PFOA) impacts murine ovarian follicle development through apoptotic signaling pathways and exhibits transgenerational effects
Sign Up to like & getrecommendations! Published in 2024 at "Human Reproduction"
DOI: 10.1093/humrep/deae108.711
Abstract: How does Perfluorooctanoic Acid (PFOA) exposure impact ovarian function and the physiological and reproductive health of subsequent offspring? PFOA exposure leads to ovarian dysfunction, characterized by follicular depletion and hormonal imbalances, and adversely affects the… read more here.
Keywords: reproductive health; pfoa; perfluorooctanoic acid; pfoa exposure ... See more keywords
PFOA exposure causes variations of Acot1 among tissues in rats, and Acot1 in serum can be potentially used as a sensitive marker for health monitoring.
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology research"
DOI: 10.1093/toxres/tfac065
Abstract: Perfluorooctanoic acid (PFOA) is a type of 8-carbon perfluoroalkyl substances (PFASs) widely used in industrial and domestic products, which now is a persistent organic pollutant (POP) found in the environment. Its structure is similar to… read more here.
Keywords: pfoa exposure; serum; variations acot1; expression ... See more keywords
PFOA-Induced Ovotoxicity Differs Between Lean and Obese Mice With Impacts on Ovarian Reproductive and DNA Damage Sensing and Repair Proteins
Sign Up to like & getrecommendations! Published in 2022 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfac104
Abstract: Abstract Perfluorooctanoic acid (PFOA) is an environmentally persistent perfluoroalkyl substance that is widely used in consumer products. Exposure to PFOA is associated with reproductive and developmental effects including endocrine disruption, delayed puberty in girls, and… read more here.
Keywords: pfoa exposure; obese mice; pfoa induced; lean obese ... See more keywords
Human Evidence of Perfluorooctanoic Acid (PFOA) Exposure on Hepatic Disease: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph191811318
Abstract: Background: Perfluorooctanoic acid (PFOA) is widely used throughout different industries, including the food industry, because it is resistant to heat and prevents water or oil from easily permeating into or contaminating materials coated by PFOA.… read more here.
Keywords: pfoa exposure; analysis; meta analysis; systematic review ... See more keywords