Perfluorooctane sulfonate aggravates CCl4‐induced hepatic fibrosis via HMGB1/TLR4/Smad signaling
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23458
Abstract: Perfluorooctane sulfonate (PFOS) is a widespread environmental pollutant and may cause a variety of adverse health effects. The hepatotoxicity of PFOS has attracted particular attention, given the fact that the liver has one of the… read more here.
Keywords: pfos; tlr4; pfos exposure; via hmgb1 ... See more keywords
Chronic PFOS Exposure Disrupts Thyroid Structure and Function in Zebrafish
Sign Up to like & getrecommendations! Published in 2018 at "Bulletin of Environmental Contamination and Toxicology"
DOI: 10.1007/s00128-018-2359-8
Abstract: Perfluorooctane sulfonic acid (PFOS), as a potential endocrine disrupting chemical, is widely detected in the environment, wildlife and human. Currently few studies have documented the effects of chronic PFOS exposure on thyroid in aquatic organisms… read more here.
Keywords: pfos; structure; function; pfos exposure ... See more keywords
Transcriptome sequencing reveals prenatal PFOS exposure on liver disorders.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental pollution"
DOI: 10.1016/j.envpol.2017.01.041
Abstract: Perfluorooctane sulfonate (PFOS), a hepatic toxicant and a potential hepatocarcinogen, is commonly used in industrial products. The widespread contamination of PFOS in human maternal and cord blood has raised concerns about its potential risks to… read more here.
Keywords: exposure; pfos; liver; transcriptome sequencing ... See more keywords
Hepatic metabolism gene expression and gut microbes in offspring, subjected to in-utero PFOS exposure and postnatal diet challenges.
Sign Up to like & getrecommendations! Published in 2022 at "Chemosphere"
DOI: 10.2139/ssrn.4176010
Abstract: We examined the changes in hepatic metabolic gene expression and gut microbiota of offspring exposed to PFOS in-utero. At GD17.5, our data showed that PFOS exposure decreased fetal bodyweights and hepatic metabolic gene expressions but… read more here.
Keywords: pfos; pfos exposed; pfos exposure; gene expression ... See more keywords
Perfluorooctane sulfonate exerts inflammatory bowel disease-like intestinal injury in rats
Sign Up to like & getrecommendations! Published in 2021 at "PeerJ"
DOI: 10.7717/peerj.10644
Abstract: Background Perfluorooctane sulfonate (PFOS), a type of perfluorinated compounds (PFCs), can induce various organ toxicity, including hepatomegaly, immunotoxicity, and gut microbiota disorder. PFCs have been associated with inflammatory bowel disease (IBD). Yet, whether PFOS exposure… read more here.
Keywords: bowel disease; inflammatory bowel; perfluorooctane sulfonate; pfos ... See more keywords