Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation
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DOI: 10.1128/mbio.02640-19
Abstract: Benzoxaboroles are under study as potential new drugs to treat malaria. One benzoxaborole, AN13762, has potent activity and promising features, but its mechanisms of action and resistance are unknown. To gain insights into these mechanisms,… read more here.
Keywords: pfpare; falciparum; level resistance; resistance ... See more keywords