Molecular basis of the inositol deacylase PGAP1 involved in quality control of GPI-AP biogenesis
Sign Up to like & getrecommendations! Published in 2024 at "Nature Communications"
DOI: 10.1038/s41467-023-44568-2
Abstract: The inositol deacylase PGAP1 initiates glycolipid remodeling required for GPI-AP sorting and secretion. Here, authors capture three PGAP1 states in a lipid environment and with products, revealing mechanisms for substrate selectivity and catalysis. The secretion… read more here.
Keywords: inositol deacylase; quality control; pgap1; deacylase pgap1 ... See more keywords
LncRNA LEMD1-AS1 relieves chondrocyte inflammation by targeting miR-944/PGAP1 in osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2084294
Abstract: ABSTRACT Osteoarthritis (OA) is a common degenerative disease characterized by reducing articular chondrocytes and destruction of joint matrix, it’s detailed pathogenesis remains unclear. Emerging evidences have demonstrated that long non-coding RNAs (lncRNAs) are closely related… read more here.
Keywords: pgap1; lemd1 as1; cell; mir 944 ... See more keywords