PGC-1a mediated mitochondrial biogenesis promotes recovery and survival of neuronal cells from cellular degeneration
Sign Up to like & getrecommendations! Published in 2024 at "Cell Death Discovery"
DOI: 10.1038/s41420-024-01953-0
Abstract: Neurodegenerative disorders are characterized by the progressive loss of structure and function of neurons, often including the death of the neuron. Previously, we reported that, by removing the cell death stimulus, dying/injured neurons could survive… read more here.
Keywords: pgc mediated; mitochondrial biogenesis; recovery; mediated mitochondrial ... See more keywords
PGC-1α-Mediated Mitochondrial Quality Control: Molecular Mechanisms and Implications for Heart Failure
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.871357
Abstract: Mitochondria with structural and functional integrity are essential for maintaining mitochondrial function and cardiac homeostasis. It is involved in the pathogenesis of many diseases. Peroxisome proliferator-activated receptor γ coactivator 1 α (PGC-1α), acted as a… read more here.
Keywords: heart failure; pgc mediated; heart; failure pgc ... See more keywords