Fine-Tuning of PGC1α Expression Regulates Cardiac Function and Longevity.
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/circresaha.119.315529
Abstract: RATIONALE PGC1α represents an attractive target interfering bioenergetics and mitochondrial homeostasis, yet multiple attempts have failed to upregulate PGC1α expression as a therapy, for instance, causing cardiomyopathy. OBJECTIVE To determine whether a fine-tuning of PGC1α… read more here.
Keywords: expression; mice; pgc1 expression; fine tuning ... See more keywords