A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis
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DOI: 10.1007/s11064-018-2588-6
Abstract: A ketogenic diet (KD; high-fat, low-carbohydrate) can benefit refractory epilepsy, but underlying mechanisms are unknown. We used mice inducibly expressing a mutated form of the mitochondrial DNA repair enzyme UNG1 (mutUNG1) to cause progressive mitochondrial… read more here.
Keywords: pgc1 sirt3; mitochondrial biogenesis; sirt3 ucp2; mutung1 mice ... See more keywords