PGC1a at the Nexus of Cancer Stem Cell Fates
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.10.391
Abstract: Cancer cells reprogram their metabolism using different strategies to meet anabolic demands to maintain growth and survival. Defining the molecular and genetic determinants of these metabolic programs, including ROS metabolism, is critical to successfully exploit… read more here.
Keywords: ros detoxification; pgc1a; cancer; melanoma progression ... See more keywords
Expression of LEP, LEPR and PGC1A genes is altered in peripheral blood mononuclear cells of patients with relapsing-remitting multiple sclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2019.577090
Abstract: Leptin (LEP) may contribute to the pathogenesis of multiple sclerosis (MS) by its immunomodulatory, proinflammatory and prooxidant effects. Therefore, plasma LEP levels and mRNA expression of five genes related to the LEP signaling pathway (LEP,… read more here.
Keywords: lepr pgc1a; relapsing remitting; pgc1a; multiple sclerosis ... See more keywords
New insights on prostate cancer progression
Sign Up to like & getrecommendations! Published in 2017 at "Cell Cycle"
DOI: 10.1080/15384101.2016.1235845
Abstract: Prostate cancer (PCa) is the fifth cause of death by cancer worldwide, second in the male population. In the European Union (EU), PCa exhibits the highest incidence among cancer types in men, and represents the… read more here.
Keywords: pgc1a; pca; expression; cancer ... See more keywords