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   Articles with "pgd2" as a keyword



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Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area

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recommendations! Published in 2019 at "Neuron"

DOI: 10.1016/j.neuron.2019.04.035

Abstract: Body temperature control is essential for survival. In mammals, thermoregulation is mediated by the preoptic area of anterior hypothalamus (POA), with ∼30% of its neurons sensitive to brain temperature change. It is still unknown whether… read more here.

Keywords: pgd2; preoptic area; temperature; thermoregulation ... See more keywords
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Prostaglandin D2 amplifies lupus disease through basophil accumulation in lymphoid organs

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recommendations! Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-03129-8

Abstract: In systemic lupus erythematosus (SLE), autoantibody production can lead to kidney damage and failure, known as lupus nephritis. Basophils amplify the synthesis of autoantibodies by accumulating in secondary lymphoid organs. Here, we show a role… read more here.

Keywords: pgd2; accumulation; lymphoid organs; disease ... See more keywords
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PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production

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recommendations! Published in 2018 at "Science Translational Medicine"

DOI: 10.1126/scitranslmed.aao0052

Abstract: RSV-induced prostaglandin D2 release contributes to disease severity by impairing IFN-λ production. RSV gives innate immunity the runaround Asthma can be exacerbated by pathogens such as respiratory syncytial virus (RSV); prostaglandin D2 (PGD2) is also… read more here.

Keywords: bronchiolitis; pgd2; production; rsv ... See more keywords
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Urine: A Lens for Asthma Pathogenesis and Treatment?

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recommendations! Published in 2020 at "American Journal of Respiratory and Critical Care Medicine"

DOI: 10.1164/rccm.202007-2899ed

Abstract: In this issue of the Journal, Kolmert and colleagues (pp. 37–53) in the U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Diseases Outcomes) Study Group report urinary eicosanoid levels from healthy control subjects, subjects with… read more here.

Keywords: medicine; treatment; pgd2; cell ... See more keywords