Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy
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DOI: 10.1038/s41598-017-18427-2
Abstract: Insulin resistance is a critical process in the initiation and progression of diabetic nephropathy (DN). Alprostadil (Prostaglandin E1, PGE1) had protective effects on renal function. However, it is unknown whether PGE1 inhibited insulin resistance in… read more here.
Keywords: insulin; via autophagy; fgf21; pge1 ... See more keywords
Lipo-PGE1 suppresses collagen production in human dermal fibroblasts via the ERK/Ets-1 signaling pathway
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DOI: 10.1371/journal.pone.0179614
Abstract: Dysregulation of collagen production contributes to various pathological processes, including tissue fibrosis as well as impaired wound healing. Lipo-prostaglandin E1 (Lipo-PGE1), a lipid microsphere-incorporated prostaglandin E1, is used as a vasodilator for the treatment of… read more here.
Keywords: lipo pge1; pge1; collagen production;
Use of Prostaglandin E1 in the Management of Congenital Diaphragmatic Hernia–A Review
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2022.911588
Abstract: Congenital diaphragmatic hernia (CDH) is a rare congenital anomaly, whose presentation is complicated by pulmonary hypertension (PH), pulmonary hypoplasia, and myocardial dysfunction, each of which have significant impact on short-term clinical management and long-term outcomes.… read more here.
Keywords: use prostaglandin; pge1; diaphragmatic hernia; congenital diaphragmatic ... See more keywords